Is it possible to have multiple security settings on a single PDF?

Using Adobe Acrobat DC Pro, can a single form have two or more security settings? 

I have an interactive form that needs to be filled in by sales and sent to customers to be checked and signed.  I need the top part secured before the form is sent to the customers to complete.

Once I create the form in Adobe Acrobat DC Pro, will the sales team have the capabilities of making changes using Reader before sending the form to the customers to complete and return?